hrp0095p1-442 | Diabetes and Insulin | ESPE2022

A Continuous Quality Improvement Effort Implemented by The Italian Network of Pediatric Diabetes Clinics

Zucchini Stefano , Bonfanti Riccardo , Lombardo Fortunato , Nicolucci Antonio , Rabbone Ivana , Schiaffini Riccardo , Vespasiani Giacomo

Pediatric diabetes management extends beyond glycemic control. A gap between guidelines and actual care exists. Standardized performance measures represent a key strategy to improve quality of care. In Italy, a non-profit initiative of continuous monitoring and quality improvement of diabetes care is in place since 2018, promoted by the ISPEDCARD association and involving the Society for Pediatric Endocrinology and diabetology (ISPED). Aim of the present work is to report the ...

hrp0084p3-1181 | Thyroid | ESPE2015

Early Discrimination between Transient and Permanent Congenital Hypothyroidism in Children with Eutopic Gland

Messina Maria Francesca , Aversa Tommaso , Salzano Giuseppina , Zirilli Giuseppina , Sferlazzas Concetta , De Luca Filippo , Lombardo Fortunato

Background: Congenital hypothyroidism (CH) is a common condition that occurs in ~1:3000–4000 live births and is one of the most common preventable cause of mental retardation with an early diagnosis and prompt pharmacological treatment. Neonatal screening has abolished this disease but 10% of children originally diagnosed with CH will have a transient form of the disorder and this percentage is increased during the last years due to a lowering of cut-off.<p class="abs...

hrp0097p1-241 | Diabetes and Insulin | ESPE2023

Association between osteocalcin and secretory function of islet beta cells in diabetic pediatric population: a pivotal study

Lombardo Fortunato , Passanisi Stefano , Lombardo Cristina , Salzano Giuseppina , Bombaci Bruno , Lugarà Cecilia , D' Amico Federica , Grasso Loredana , Aguennouz M'Hammed , Catalano Antonino , Valenzise Mariella

Background: Osteocalcin plays a role in glucose metabolism in mice, but its relevance in human energetic metabolism is controversial. Few data are available on osteocalcin in pediatric patients with T1DM. The aim of our monocenter observational study was to evaluate the role of the main remodelling bone biomarkers in the regulation of glucose metabolism at the time of type 1 diabetes diagnosis and to evaluate their potential relationship with insulin sensitivi...